Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) [ICH1130UL] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) [ICH1130UL] ichorbio

catalog :

ICH1130UL

quantity :

5 mg

price :

312 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RA3-6B2

reactivity :

human, mouse

application :

western blot

more info or order :

ichorbio product webpage

product information

Product Type :

Ultra Low Endotoxin

ichorbio Cat Number :

ICH1130UL

Page Title :

Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) [ICH1130UL] ichorbio

Page Heading :

Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) [ICH1130UL]

Page Heading :

Bulk anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2)

Product Benefits :

ichorbio's anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD45R

Clone :

RA3-6B2

Size1 :

5 mg

Academic Price1 :

312 GBP

Size2 :

25mg

Academic Price2 :

832

Size3 :

50mg

Academic Price3 :

1352

Size4 :

100mg

Academic Price4 :

2080

Isotype :

Rat IgG2a

Other names :

Leukocyte common antigen, L-CA, T200, CD45, Receptor-type tyrosine-protein phosphatase C, PTPRC, B220

UniProt :

P08575

Host :

Rat

Species Reactivity :

Mouse, Human

Specificity :

Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD45R antigen is present on mouse B-cells, B-cell precursors, T cell subset, NK cell subsets .

Background :

CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.

Immunogen :

Abelson murine leukemia virus-induced pre-B tumor cells

Concentration :

≥ 2.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>98% by SDS-PAGE and HPLC

Endotoxin :

≤ 0.75 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 1%

IMPACT Pathogen Test :

We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Rat parvovirus Lymphocytic choriomeningitis virus Rat cytomegalovirus Sendai virus Rat coronavirus Sialodacryoadenitis virus Rat minute virus Seoul virus Mouse adenovirus Reovirus 3 Rat theilovirus

Storage :

anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Functional Assays

Application Notes :

Functional Assay: In vivo treatment with Rat Anti-Mouse CD45R (Clone RA3-6B2) reduces the number of T and B cells and modifies their functional activity. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2a In Vivo Isotype Control - Ultra Low Endotoxin [1-1] (ICH2244UL)

Related Antibody :

Anti-CD45R In Vivo Antibody - Low Endotoxin [RA3-6B2] (ICH1130)

Antibodies against the same target :

Anti-CD45 In Vivo Antibody - Low Endotoxin [I3/2.3] (ICH1057)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage