Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) [ICH1130] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) [ICH1130] ichorbio

catalog :

ICH1130

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RA3-6B2

reactivity :

human, mouse

application :

western blot

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1130

Page Title :

Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) [ICH1130] ichorbio

Page Heading :

Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) [ICH1130]

Page Heading :

Bulk anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2)

Product Benefits :

ichorbio's anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD45R

Clone :

RA3-6B2

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2a

Other names :

Leukocyte common antigen, L-CA, T200, CD45, Receptor-type tyrosine-protein phosphatase C, PTPRC, B220

UniProt :

P08575

Host :

Rat

Species Reactivity :

Mouse, Human

Specificity :

Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD45R antigen is present on mouse B-cells, B-cell precursors, T cell subset, NK cell subsets .

Background :

CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.

Immunogen :

Abelson murine leukemia virus-induced pre-B tumor cells

Concentration :

0.5 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) is stable for at least four (4) weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Functional Assays

Application Notes :

Functional Assay: In vivo treatment with Rat Anti-Mouse CD45R (Clone RA3-6B2) reduces the number of T and B cells and modifies their functional activity. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)

Related Antibody :

Anti-CD45R In Vivo Antibody - Ultra Low Endotoxin [RA3-6B2] (ICH1130UL)

Antibodies against the same target :

Anti-CD45 In Vivo Antibody - Low Endotoxin [I3/2.3] (ICH1057)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage