product summary
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company name :
ichorbio
product type :
antibody
product name :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22) [ICH1127] ichorbio
catalog :
ICH1127
quantity :
1 mg
price :
80 GBP
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MP6-XT22
reactivity :
mouse
application :
western blot
more info or order :
product information
Product Type :
Low Endotoxin
ichorbio Cat Number :
ICH1127
Page Title :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22) [ICH1127] ichorbio
Page Heading :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22) [ICH1127]
Page Heading :
Bulk anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22)
Product Benefits :
ichorbio's anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
Target :
TNF alpha
Clone :
MP6-XT22
Size1 :
1 mg
Academic Price1 :
80 GBP
Size2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
Isotype :
Rat IgG1
Other names :
Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
UniProt :
P06804
Host :
Rat
Species Reactivity :
Mouse
Specificity :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22) recognizes an epitope on Mouse TNFalpha
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background :
The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis.
Immunogen :
Purified Recombinant Mouse TNF-alpha (>98%)
Concentration :
1.0 - 5.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>95% by SDS-PAGE and HPLC
Endotoxin :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
Storage :
anti-TNF alpha In Vivo Antibody - Low Endotoxin (MP6-XT22) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications :
Western Blot
Application Notes :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG1 Isotype Control for In Vivo - Low Endotoxin [GL113] (ICH2246)
Antibodies against the same target :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin [TN3-19.12] (ICH1136) , Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin [TN3-19.12 ] (ICH1136UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK