Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) [ICH1124] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) [ICH1124] ichorbio

catalog :

ICH1124

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

MIB-5E9.1

application :

western blot, immunoprecipitation

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1124

Page Title :

Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) [ICH1124] ichorbio

Page Heading :

Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) [ICH1124]

Page Heading :

Bulk anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1)

Product Benefits :

ichorbio's anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

IFN beta

Clone :

MIB-5E9.1

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Armenian Hamster IgG

Other names :

IFN-b, IFN-beta, Type-1 interferon, Interferon beta

Host :

Armenian Hamster

Species Reactivity :

Mouse

Specificity :

Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) recognizes Mouse IFN beta

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

Fibroblasts & epithelial cells

Background :

Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Applications :

Immunoprecipitation, Western Blot

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)

Antibodies against the same target :

Anti-IFN beta In Vivo Antibody - Low Endotoxin [HDB-4A7] (ICH1110) , Anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin [HDB-4A7] (ICH1110UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage