product summary
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company name :
ichorbio
product type :
antibody
product name :
Anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) [ICH1119] ichorbio
catalog :
ICH1119
quantity :
0.5 mg
price :
160 GBP
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
JES6-1A12
reactivity :
mouse
application :
western blot, immunoprecipitation
more info or order :
product information
Product Type :
Low Endotoxin
ichorbio Cat Number :
ICH1119
Page Title :
Anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) [ICH1119] ichorbio
Page Heading :
Anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) [ICH1119]
Page Heading :
Bulk anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12)
Product Benefits :
ichorbio's anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
Target :
IL-2
Clone :
JES6-1A12
Size1 :
0.5 mg
Academic Price1 :
160 GBP
Size2 :
1mg
Academic Price2 :
240
Isotype :
Rat IgG2a
Other names :
Interleukin-2, Il2, T-cell growth factor, TCGF
UniProt :
P04351
Host :
Rat
Species Reactivity :
Mouse
Specificity :
Anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) recognizes an epitope on Mouse IL-2
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background :
Interleukin-2 (IL-2) is a potent T-cell mitogenic cytokine that functions as a primary regulator of T cell homeostasis and has been considered a prime candidate immunotherapeutics, both for increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses. IL-2 plays a key role in setting the balance between immunity and tolerance. This cytokine has a dual role as the regulator of the two main phases of the immune response (proliferative and suppressive). IL-2 also stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. The JES6-1A12 antibody has been shown to neutralize IL-2 in vivo.
Immunogen :
Purified Recombinant Mouse IL-2 (>98%)
Concentration :
1.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>95% by SDS-PAGE and HPLC
Endotoxin :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
Storage :
anti-IL-2 In Vivo Antibody - Low Endotoxin (JES6-1A12) is stable when stored at 2-8°C. Do not freeze.
Applications :
Immunoprecipitation, Western Blot
Application Notes :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK