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company name :
ichorbio
product type :
antibody
product name :
Anti-CD44 In Vivo Antibody - Low Endotoxin (IM7) [ICH1115] ichorbio
catalog :
ICH1115
quantity :
1 mg
price :
80 GBP
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
IM7
reactivity :
mouse
application :
western blot, immunoprecipitation
more info or order :
ichorbio product webpage
product information
Product Type :
Low Endotoxin
ichorbio Cat Number :
ICH1115
Page Title :
Anti-CD44 In Vivo Antibody - Low Endotoxin (IM7) [ICH1115] ichorbio
Page Heading :
Anti-CD44 In Vivo Antibody - Low Endotoxin (IM7) [ICH1115]
Page Heading :
Bulk anti-CD44 In Vivo Antibody - Low Endotoxin (IM7)
Product Benefits :
ichorbio's anti-CD44 In Vivo Antibody - Low Endotoxin (IM7) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
Target :
CD44
Clone :
IM7
Size1 :
1 mg
Academic Price1 :
80 GBP
Size2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
Isotype :
Rat IgG2b
Other names :
Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24, Ly-24, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I
UniProt :
P15379
Host :
Rat
Species Reactivity :
Mouse
Specificity :
Anti-CD44 In Vivo Antibody - Low Endotoxin (IM7) recognizes an epitope common to alloantigens & all isoforms of CD44, that is located between amino acids 145 and 186
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
The CD44 antigen is present on B-cells, monocytes, macrophages and certain subsets of thymocytes and peripheral T-cells. Mice with the Ly-24.1 allotype have high densities of CD44+ T-cells, while Ly-24.2 strains are low expressors. The antibody cross reacts with: Ms+, Hu+, Bov+, Mky+, Bab+, Dog+, Cat, Porcine
Background :
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Clone IM7 antibody has been shown to neutralize CD44 in vivo
Immunogen :
Dexamethasone-induced myeloid leukemia M1 cells
Concentration :
0.5 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>95% by SDS-PAGE and HPLC
Endotoxin :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
Storage :
anti-CD44 In Vivo Antibody - Low Endotoxin (IM7) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications :
Immunoprecipitation, Western Blot
Application Notes :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
Related Antibody :
Anti-CD44 In Vivo Antibody - Ultra Low Endotoxin [IM7] (ICH1115UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
ichorbio product webpage
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK