Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) [ICH1101] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) [ICH1101] ichorbio

catalog :

ICH1101

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

BE29G1

reactivity :

mouse

application :

western blot, neutralization, immunoprecipitation

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1101

Page Title :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) [ICH1101] ichorbio

Page Heading :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) [ICH1101]

Page Heading :

Bulk anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1)

Product Benefits :

ichorbio's anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

ICAM-1

Clone :

BE29G1

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2a

Other names :

Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54

UniProt :

P13597

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).

Antigen Distribution :

The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.

Background :

Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies

Immunogen :

Purified Recombinant Mouse ICAM-1 (>98%)

Concentration :

0.5 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Immunoprecipitation, Western Blot, Blocking

Application Notes :

Blocking: This antibody blocks the binding LFA-1 (CD11a/CD18) to ICAM-1. The antibody is suitable for studies of inflammation, lymphocyte differentiation, and lymphocyte activation. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)

Antibodies against the same target :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin [15.2] (ICH1027)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage