antibody

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) [ICH1084UL] ichorbio

ICH1084UL

5 mg

312 GBP

monoclonal

golden hamster

nonconjugated

9H10

western blot, neutralization

ICH1084UL

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) [ICH1084UL] ichorbio

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) [ICH1084UL]

Bulk anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10)

ichorbio's anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.

CTLA-4

9H10

5 mg

312 GBP

25mg

832

50mg

1352

100mg

2080

Syrian Hamster IgG

Ctla4, Cytotoxic T-lymphocyte protein 4, CD152

P09793

Syrian Hamster

Mouse

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Activated T cells

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding.

Mouse CTLA-4-human IgG1 fusion protein

1.0 - 5.0 mg/ml

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

>98% by SDS-PAGE and HPLC

≤ 0.5 EU/mg as determined by the LAL method

Aggregation level ≤ 1%

We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Hamster parvovirus Lymphocytic choriomeningitis Minute virus of mice Theiler's murine encephalomyelitis virus Sendai virus Reovirus 3 Hantaan virus

anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Western Blot, Blocking

Each investigator should determine their own optimal working dilution for specific applications.

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [9H10] (ICH1084)

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [9D9] (ICH1096) , Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin [9D9] (ICH1096UL) , Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [UC10-4F10-11] (ICH1085)

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Contact for industrial pricing