Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) [ICH1084] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) [ICH1084] ichorbio

catalog :

ICH1084

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

golden hamster

conjugate :

nonconjugated

clone name :

9H10

reactivity :

mouse

application :

western blot, neutralization

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1084

Page Title :

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) [ICH1084] ichorbio

Page Heading :

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) [ICH1084]

Page Heading :

Bulk anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10)

Product Benefits :

ichorbio's anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CTLA-4

Clone :

9H10

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Syrian Hamster IgG

Other names :

Ctla4, Cytotoxic T-lymphocyte protein 4, CD152

UniProt :

P09793

Host :

Syrian Hamster

Species Reactivity :

Mouse

Specificity :

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

Activated T cells

Background :

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding.

Immunogen :

Mouse CTLA-4-human IgG1 fusion protein

Concentration :

1.0 - 5.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Blocking

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Related Antibody :

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin [9H10] (ICH1084UL)

Antibodies against the same target :

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [UC10-4F10-11] (ICH1085) , Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [9D9] (ICH1096) , Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin [9D9] (ICH1096UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage