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company name :
ichorbio
product type :
antibody
product name :
Anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) [ICH1071] ichorbio
catalog :
ICH1071
quantity :
0.5 mg
price :
160 GBP
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
A7R34
reactivity :
mouse
application :
western blot, neutralization, immunoprecipitation
more info or order :
ichorbio product webpage
product information
Product Type :
Low Endotoxin
ichorbio Cat Number :
ICH1071
Page Title :
Anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) [ICH1071] ichorbio
Page Heading :
Anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) [ICH1071]
Page Heading :
Bulk anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34)
Product Benefits :
ichorbio's anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
Target :
CD127
Clone :
A7R34
Size1 :
0.5 mg
Academic Price1 :
160 GBP
Size2 :
1mg
Academic Price2 :
240
Isotype :
Rat IgG2a
Other names :
Interleukin-7 receptor subunit alpha, Il7r, IL-7R subunit alpha, IL-7R-alpha, IL-7RA
UniProt :
P16872
Host :
Rat
Species Reactivity :
Mouse
Specificity :
Anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) recognizes an epitope on Mouse CD127
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background :
IL-7 receptor alpha (IL-7Ra), also known as CD127, is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, natural killer (NK) cells, naïve T cells and memory CD4+ and CD8+ T cells. IL-7Ra is also expressed on non-immune somatic cells such as intestinal colorectal and renal carcinoma cell lines and keratinocytes. IL-7Ralpha displays a synergistic decrease in the number of T-cell, NK-cell and multipotent progenitors in the thymus, indicating that these distinct survival pathways converge to promote the development of multipotent lymphoid progenitors.
Immunogen :
IL-7Ra-IgG1 fusion protein
Concentration :
1.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>95% by SDS-PAGE and HPLC
Endotoxin :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
Storage :
anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) is stable when stored sterile at 2-8°C. Do not freeze.
Applications :
Immunoprecipitation, Western Blot, Blocking, Functional Assays
Application Notes :
Blocking: Clone A7R34 is able to block clone SB/199 binding to IL-7R. Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
ichorbio product webpage
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK