Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) [ICH1069] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) [ICH1069] ichorbio

catalog :

ICH1069

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

55R-593

reactivity :

mouse

application :

western blot, immunoprecipitation

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1069

Page Title :

Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) [ICH1069] ichorbio

Page Heading :

Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) [ICH1069]

Page Heading :

Bulk anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593)

Product Benefits :

ichorbio's anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD120a

Clone :

55R-593

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Armenian Hamster IgG1

Other names :

Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60

UniProt :

P25118

Host :

Armenian Hamster

Species Reactivity :

Mouse

Specificity :

Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) recognizes Mouse CD120A

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

Variety of cell types at low levels

Background :

Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

Immunogen :

E. coli-expressed extracellular domain of the mouse TNFRI protein

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD120a In Vivo Antibody - Low Endotoxin (55R-593) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C.

Applications :

Immunoprecipitation, Western Blot

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)

Antibodies against the same target :

Anti-CD120a In Vivo Antibody - Low Endotoxin [55R-170] (ICH1094)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage