antibody

Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) [ICH1068UL] ichorbio

ICH1068UL

5 mg

312 GBP

monoclonal

rat

nonconjugated

AFS98

western blot, neutralization

ICH1068UL

Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) [ICH1068UL] ichorbio

Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) [ICH1068UL]

Bulk anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98)

ichorbio's anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.

CD115

AFS98

5 mg

312 GBP

25mg

832

50mg

1352

100mg

2080

Rat IgG2a

Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms

P09581

Rat

Mouse

Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) recognizes an epitope on Mouse M-CSFR

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts

Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.

Purified Recombinant Mouse M-CSFR

1.0 - 5.0 mg/ml

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

>98% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Aggregation level ≤ 1%

We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Rat parvovirus Lymphocytic choriomeningitis virus Rat cytomegalovirus Sendai virus Rat coronavirus Sialodacryoadenitis virus Rat minute virus Seoul virus Mouse adenovirus Reovirus 3 Rat theilovirus

anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.

Western Blot, Blocking, Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.

Rat IgG2a In Vivo Isotype Control - Ultra Low Endotoxin [1-1] (ICH2244UL)

Anti-CD115 In Vivo Antibody - Low Endotoxin [AFS98] (ICH1068)

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Contact for industrial pricing