Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) [ICH1068] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) [ICH1068] ichorbio

catalog :

ICH1068

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

AFS98

reactivity :

mouse

application :

western blot, neutralization

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1068

Page Title :

Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) [ICH1068] ichorbio

Page Heading :

Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) [ICH1068]

Page Heading :

Bulk anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98)

Product Benefits :

ichorbio's anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD115

Clone :

AFS98

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2a

Other names :

Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms

UniProt :

P09581

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) recognizes an epitope on Mouse M-CSFR

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts

Background :

Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.

Immunogen :

Purified Recombinant Mouse M-CSFR

Concentration :

1.0 - 5.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.

Applications :

Western Blot, Blocking, Functional Assays

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)

Related Antibody :

Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin [AFS98] (ICH1068UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage