Anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) [ICH1061] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) [ICH1061] ichorbio

catalog :

ICH1061

quantity :

0.5 mg

price :

240 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

FR70

reactivity :

mouse

application :

western blot, neutralization, immunoprecipitation

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1061

Page Title :

Anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) [ICH1061] ichorbio

Page Heading :

Anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) [ICH1061]

Page Heading :

Bulk anti-CD70 In Vivo Antibody - Low Endotoxin (FR70)

Product Benefits :

ichorbio's anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD70

Clone :

FR70

Size1 :

0.5 mg

Academic Price1 :

240 GBP

Isotype :

Rat IgG2b

Other names :

CD27 ligand, Cd27l, Cd27lg, Tnfsf7

UniProt :

O55237

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) recognizes an epitope on Mouse CD70

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD70 antigen is expressed by activated B cells and some activated T cells.

Background :

CD70 is a 30-33 kDa type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Immunogen :

BALB/c mouse B lymphoma A20.J2

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD70 In Vivo Antibody - Low Endotoxin (FR70) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Immunoprecipitation, Western Blot, Blocking

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage