Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) [ICH1059] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) [ICH1059] ichorbio

catalog :

ICH1059

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

YN1/1.7.4

reactivity :

mouse

application :

western blot

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1059

Page Title :

Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) [ICH1059] ichorbio

Page Heading :

Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) [ICH1059]

Page Heading :

Bulk anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4)

Product Benefits :

ichorbio's anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD54

Clone :

YN1/1.7.4

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2b

Other names :

Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10

UniProt :

P13597

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) recognizes an epitope on Mouse ICAM-1

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.

Background :

Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.

Immunogen :

Mouse NS-1 cells

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Functional Assays

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage