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company name :
ichorbio
product type :
antibody
product name :
Anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7) [ICH1044] ichorbio
catalog :
ICH1044
quantity :
1 mg
price :
80 GBP
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
53-6.7
reactivity :
mouse
application :
western blot, immunoprecipitation
more info or order :
product information
Product Type :
Low Endotoxin
ichorbio Cat Number :
ICH1044
Page Title :
Anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7) [ICH1044] ichorbio
Page Heading :
Anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7) [ICH1044]
Page Heading :
Bulk anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7)
Product Benefits :
ichorbio's anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
Target :
CD8a
Clone :
53-6.7
Size1 :
1 mg
Academic Price1 :
80 GBP
Size2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
Isotype :
Rat IgG2a
Other names :
CD8 alpha chain, Lyt-2, Lyt2
UniProt :
P01731
Host :
Rat
Species Reactivity :
Mouse
Specificity :
Anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7) recognizes Lyt 2, lymphocyte differentiation antigen. The antibody precipitates 44 kDa and 33 kDa proteins and reacts with non-polymorphic determinant.
Antigen Distribution :
Present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic cells. CD8 participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck.
Background :
CD8, a.k.a Lyt-2, Ly-2, or T8, consists of disulfide-linked A and β chains that form the A(CD8a)/β(CD8b) heterodimer and A/A homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 A/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR A/β T cells.
Immunogen :
Mouse thymus or spleen
Concentration :
1.0 - 5.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>95% by SDS-PAGE and HPLC
Endotoxin :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
Storage :
anti-CD8a In Vivo Antibody - Low Endotoxin (53-6.7) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications :
Immunoprecipitation, Western Blot
Application Notes :
Immunoprecipitation: Rat Anti-Mouse CD8a (Clone 53-6.7) precipitates 44 kDa and 33 kDa proteins. Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Related Antibody :
Anti-CD8a In Vivo Antibody - Ultra Low Endotoxin [53-6.7] (ICH1044UL)
Antibodies against the same target :
Anti-CD8a In Vivo Antibody - Low Endotoxin [2.43] (ICH1045) , Anti-CD8a In Vivo Antibody - Ultra Low Endotoxin [2.43] (ICH1045UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK