Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) [ICH1042UL] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) [ICH1042UL] ichorbio

catalog :

ICH1042UL

quantity :

5 mg

price :

312 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GK1.5

reactivity :

human

application :

western blot, neutralization

more info or order :

ichorbio product webpage

product information

Product Type :

Ultra Low Endotoxin

ichorbio Cat Number :

ICH1042UL

Page Title :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) [ICH1042UL] ichorbio

Page Heading :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) [ICH1042UL]

Page Heading :

Bulk anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5)

Product Benefits :

ichorbio's anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD4

Clone :

GK1.5

Size1 :

5 mg

Academic Price1 :

312 GBP

Size2 :

25mg

Academic Price2 :

832

Size3 :

50mg

Academic Price3 :

1352

Size4 :

100mg

Academic Price4 :

2080

Isotype :

Rat IgG2b

Other names :

T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) recognizes an epitope on Mouse CD4

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.

Background :

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.

Immunogen :

Mouse CTL clone V4

Concentration :

≥ 2.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>98% by SDS-PAGE and HPLC

Endotoxin :

≤ 0.75 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 1%

IMPACT Pathogen Test :

We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Rat parvovirus Lymphocytic choriomeningitis virus Rat cytomegalovirus Sendai virus Rat coronavirus Sialodacryoadenitis virus Rat minute virus Seoul virus Mouse adenovirus Reovirus 3 Rat theilovirus

Storage :

anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (GK1.5) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Blocking

Application Notes :

Blocking: The GK1.5 antibody is able to block CD4 mediated cell adhesion and T cell activation. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2b In Vivo Isotype Control - Ultra Low Endotoxin [1-2] (ICH2243UL)

Related Antibody :

Anti-CD4 In Vivo Antibody - Low Endotoxin [GK1.5] (ICH1042)

Antibodies against the same target :

Anti-CD4 In Vivo Antibody - Low Endotoxin [RPA-T4] (ICH1004) , Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin [RPA-T4] (ICH1004UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage