Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) [ICH1042] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) [ICH1042] ichorbio

catalog :

ICH1042

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GK1.5

reactivity :

human

application :

western blot, neutralization

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1042

Page Title :

Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) [ICH1042] ichorbio

Page Heading :

Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) [ICH1042]

Page Heading :

Bulk anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5)

Product Benefits :

ichorbio's anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD4

Clone :

GK1.5

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2b

Other names :

T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) recognizes an epitope on Mouse CD4

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.

Background :

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.

Immunogen :

Mouse CTL clone V4

Concentration :

≥ 2.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Blocking

Application Notes :

Blocking: Anti-Mouse CD4 (clone GK1.5) is useful for In vitro and In vivo studies of T-helper cell functions including blocking of ligand binding and T-helper cell activation. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)

Related Antibody :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin [GK1.5] (ICH1042UL)

Antibodies against the same target :

Anti-CD4 In Vivo Antibody - Low Endotoxin [RPA-T4] (ICH1004) , Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin [RPA-T4] (ICH1004UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage