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company name :
ichorbio
product type :
antibody
product name :
Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) [ICH1041UL] ichorbio
catalog :
ICH1041UL
quantity :
5 mg
price :
312 GBP
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
145-2C11
reactivity :
human
application :
western blot, immunohistochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
product information
Product Type :
Ultra Low Endotoxin
ichorbio Cat Number :
ICH1041UL
Page Title :
Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) [ICH1041UL] ichorbio
Page Heading :
Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) [ICH1041UL]
Page Heading :
Bulk anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11)
Product Benefits :
ichorbio's anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target :
CD3e
Clone :
145-2C11
Size1 :
5 mg
Academic Price1 :
312 GBP
Size2 :
25mg
Academic Price2 :
832
Size3 :
50mg
Academic Price3 :
1352
Size4 :
100mg
Academic Price4 :
2080
Isotype :
Armenian Hamster IgG
Other names :
T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e
Host :
Armenian Hamster
Species Reactivity :
Mouse
Specificity :
Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) recognizes an epitope on Mouse CD3e
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
The CD3 complex is present on thymocytes (differentiation dependent), mature T cells, NK-T cells of all mouse strains tested.
Background :
CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Immunogen :
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Concentration :
1.0 - 5.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>98% by SDS-PAGE and HPLC
Endotoxin :
≤ 0.75 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 1%
IMPACT Pathogen Test :
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Hamster parvovirus Lymphocytic choriomeningitis Minute virus of mice Theiler's murine encephalomyelitis virus Sendai virus Reovirus 3 Hantaan virus
Storage :
anti-CD3e In Vivo Antibody - Ultra Low Endotoxin (145-2C11) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications :
IHC (Frozen), Flow Cytometry, Immunoprecipitation, Western Blot, In vivo Depletion, Blocking
Application Notes :
Blocking: The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL)
Related Antibody :
Anti-CD3e In Vivo Antibody - Low Endotoxin [145-2C11] (ICH1041)
Antibodies against the same target :
Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin [500A2] (ICH1040UL) , Anti-CD3e In Vivo Antibody - Low Endotoxin [500A2] (ICH1040)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK