Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) [ICH1041] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) [ICH1041] ichorbio

catalog :

ICH1041

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

145-2C11

reactivity :

human

application :

neutralization, immunoprecipitation

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1041

Page Title :

Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) [ICH1041] ichorbio

Page Heading :

Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) [ICH1041]

Page Heading :

Bulk anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11)

Product Benefits :

ichorbio's anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD3e

Clone :

145-2C11

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Armenian Hamster IgG

Other names :

T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e

Host :

Armenian Hamster

Species Reactivity :

Mouse

Specificity :

Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) recognizes an epitope on Mouse CD3e

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD3 complex is present on thymocytes (differentiation dependent), mature T cells, NK-T cells of all mouse strains tested.

Background :

CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Immunogen :

H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Immunoprecipitation, Blocking

Application Notes :

Blocking: The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)

Related Antibody :

Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin [145-2C11] (ICH1041UL)

Antibodies against the same target :

Anti-CD3e In Vivo Antibody - Low Endotoxin [500A2] (ICH1040) , Anti-CD3e In Vivo Antibody - Ultra Low Endotoxin [500A2] (ICH1040UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage