Anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) [ICH1039] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) [ICH1039] ichorbio

catalog :

ICH1039

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

17A2

reactivity :

human

application :

western blot, immunoprecipitation

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1039

Page Title :

Anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) [ICH1039] ichorbio

Page Heading :

Anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) [ICH1039]

Page Heading :

Bulk anti-CD3 In Vivo Antibody - Low Endotoxin (17A2)

Product Benefits :

ichorbio's anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD3

Clone :

17A2

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2b

Other names :

T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e, Cd3g, T3 gamma chain, CD3 gamma chain

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) recognizes an epitope on Mouse CD3. The 17A2 clone reacts with the epsilon and gamma chains and not delta nor zeta of CD3.

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD3 complex is present on thymocytes and mature T-lymphocytes of all mouse strains tested.

Background :

CD3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR A/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Immunogen :

gamma/delta TCR-positive T-T hybridoma D1

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD3 In Vivo Antibody - Low Endotoxin (17A2) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Immunoprecipitation, Western Blot

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)

Antibodies against the same target :

Anti-CD3 In Vivo Antibody - Low Endotoxin [UCHT-1] (ICH1002) , Anti-CD3 In Vivo Antibody - Low Endotoxin [HIT3a] (ICH1003)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage