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company name :
ichorbio
product type :
antibody
product name :
Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) [ICH1037UL] ichorbio
catalog :
ICH1037UL
quantity :
5 mg
price :
312 GBP
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
16-10A1
reactivity :
mouse
application :
western blot
more info or order :
product information
Product Type :
Ultra Low Endotoxin
ichorbio Cat Number :
ICH1037UL
Page Title :
Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) [ICH1037UL] ichorbio
Page Heading :
Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) [ICH1037UL]
Page Heading :
Bulk anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1)
Product Benefits :
ichorbio's anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target :
CD80
Clone :
16-10A1
Size1 :
5 mg
Academic Price1 :
312 GBP
Size2 :
25mg
Academic Price2 :
832
Size3 :
50mg
Academic Price3 :
1352
Size4 :
100mg
Academic Price4 :
2080
Isotype :
Armenian Hamster IgG
Other names :
Activation B7-1 antigen, B7
UniProt :
Q00609
Host :
Armenian Hamster
Species Reactivity :
Mouse
Specificity :
Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells.
Background :
CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
Immunogen :
Purified Recombinant Mouse CD80 (>98%)
Concentration :
≥ 2.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>98% by SDS-PAGE and HPLC
Endotoxin :
≤ 0.75 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 1%
IMPACT Pathogen Test :
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Hamster parvovirus Lymphocytic choriomeningitis Minute virus of mice Theiler's murine encephalomyelitis virus Sendai virus Reovirus 3 Hantaan virus
Storage :
anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications :
Western Blot
Application Notes :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL)
Related Antibody :
Anti-CD80 In Vivo Antibody - Low Endotoxin [16-10A1] (ICH1037)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
company information
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
headquarters: UK