Anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) [ICH1036] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) [ICH1036] ichorbio

catalog :

ICH1036

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

3H3

reactivity :

mouse

application :

western blot

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1036

Page Title :

Anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) [ICH1036] ichorbio

Page Heading :

Anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) [ICH1036]

Page Heading :

Bulk anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3)

Product Benefits :

ichorbio's anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

4-1BB

Clone :

3H3

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Rat IgG2a

Other names :

4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137

UniProt :

P20334

Host :

Rat

Species Reactivity :

Mouse

Specificity :

Anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) recognizes an epitope on Mouse 4-1BB

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

Activated T cells and B cells

Background :

4-1BB (CD137) is a costimulatory molecule expressed on the surface of activated T cells and plays a role in T-cell-mediated proliferative response. 4-1BB signal regulates CD28 co-stimulation in the targeted subset cells to favor Th1 development and maintain long-term cell growth. 4-1BB is also expressed on dendritic cells (DCs) and controls the duration, DC-T interaction, and, therefore, immunogenicity. Clone 3H3 antibody is an agonistic antibody that has been shown to stimulate 4-1BB signaling in vivo.

Immunogen :

Unknown

Concentration :

1.0 - 5.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-4-1BB In Vivo Antibody - Low Endotoxin (3H3) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Functional Assays

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)

Related Antibody :

Anti-4-1BB In Vivo Antibody - Ultra Low Endotoxin [3H3] (ICH1036UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage