Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) [ICH1027] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) [ICH1027] ichorbio

catalog :

ICH1027

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15.2

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1027

Page Title :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) [ICH1027] ichorbio

Page Heading :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) [ICH1027]

Page Heading :

Bulk anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2)

Product Benefits :

ichorbio's anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

ICAM-1

Clone :

15.2

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Mouse IgG1

Other names :

Intercellular adhesion molecule 1, ICAM1, Major group rhinovirus receptor, CD54

UniProt :

P05362

Host :

Mouse

Species Reactivity :

Human

Specificity :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) recognizes an epitope on Human ICAM-1

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD54 antigen is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinoviruses and malaria.

Background :

Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.

Immunogen :

Human infant thymocytes and Sezary cells

Concentration :

1.0 - 5.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

<1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

IHC (FFPE), Flow Cytometry, Immunoprecipitation, Western Blot

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)

Antibodies against the same target :

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin [BE29G1] (ICH1101)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage