Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) [ICH1004UL] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) [ICH1004UL] ichorbio

catalog :

ICH1004UL

quantity :

5 mg

price :

312 GBP

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RPA-T4

reactivity :

human

application :

western blot, neutralization

more info or order :

ichorbio product webpage

product information

Product Type :

Ultra Low Endotoxin

ichorbio Cat Number :

ICH1004UL

Page Title :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) [ICH1004UL] ichorbio

Page Heading :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) [ICH1004UL]

Page Heading :

Bulk anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4)

Product Benefits :

ichorbio's anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD4

Clone :

RPA-T4

Size1 :

5 mg

Academic Price1 :

312 GBP

Size2 :

25mg

Academic Price2 :

832

Size3 :

50mg

Academic Price3 :

1352

Size4 :

100mg

Academic Price4 :

2080

Isotype :

Mouse IgG1

Other names :

T-cell surface antigen T4/Leu-3

UniProt :

P01730

Host :

Mouse

Species Reactivity :

Human

Specificity :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) recognizes Human CD4. Anti-Human CD4 recognizes a human surface glycoprotein (Mr 55-62 kDa) present on T-helper/inducer lymphocytes and monocytes. Anti-CD4 blocks various immunoregulatory functions.

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD4 antigen is present on the helper/inducer subset of T-lymphocytes. CD4 positive cells make up approximately 25-60% of normal peripheral blood lymphoctes and 80-90% of normal thymocytes. CD4 has also been shown to be present in low density on monocytes and intracellularly in monocytes and macrophages.

Background :

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.

Concentration :

1.0 - 5.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>98% by SDS-PAGE and HPLC

Endotoxin :

≤ 0.75 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 1%

IMPACT Pathogen Test :

We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp. Mycoplasma pulmonis Sendai virus Mouse hepatitis virus Pneumonia virus of mice Minute virus of mice Mouse parvovirus (MPV1-5) Theiler's murine encephalomyelitis virus Murine norovirus Reovirus 3 Mouse rotavirus Ectromelia virus Lymphocytic choriomeningitis virus Polyoma virus Lactate dehydrogenase-elevating virus Mouse adenovirus (MAD1, MAD2) Mouse cytomegalovirus K virus Mouse thymic virus Hantaan virus Corynebacterium bovis Corynebacterium spp. (HAC2)

Storage :

anti-CD4 In Vivo Antibody - Ultra Low Endotoxin (RPA-T4) is stable when stored at 2-8°C. TFor long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Blocking, Functional Assays

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Mouse IgG1 Isotype Control for In Vivo - Ultra Low Endotoxin [HKSP] (ICH2247UL)

Antibodies against the same target :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin [GK1.5] (ICH1042UL) , Anti-CD4 In Vivo Antibody - Low Endotoxin [GK1.5] (ICH1042)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage