Anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) [ICH1004] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) [ICH1004] ichorbio

catalog :

ICH1004

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RPA-T4

reactivity :

human

application :

immunohistochemistry, neutralization, flow cytometry

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1004

Page Title :

Anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) [ICH1004] ichorbio

Page Heading :

Anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) [ICH1004]

Page Heading :

Bulk anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4)

Product Benefits :

ichorbio's anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD4

Clone :

RPA-T4

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Mouse IgG1

Other names :

T-cell surface antigen T4/Leu-3

UniProt :

P01730

Host :

Mouse

Species Reactivity :

Human

Specificity :

Anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) recognizes Human CD4. Anti-Human CD4 recognizes a human surface glycoprotein (Mr 55-62 kDa) present on T-helper/inducer lymphocytes and monocytes. Anti-CD4 blocks various immunoregulatory functions.

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD4 antigen is present on the helper/inducer subset of T-lymphocytes. CD4 positive cells make up approximately 25-60% of normal peripheral blood lymphoctes and 80-90% of normal thymocytes. CD4 has also been shown to be present in low density on monocytes and intracellularly in monocytes and macrophages.

Background :

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.

Concentration :

1.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

<1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD4 In Vivo Antibody - Low Endotoxin (RPA-T4) is stable when stored at 2-8°C. Do not freeze. This antibody is

Applications :

IHC (FFPE), Flow Cytometry, Blocking, Functional Assays

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)

Related Antibody :

Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin [RPA-T4] (ICH1004UL)

Antibodies against the same target :

Anti-CD4 In Vivo Antibody - Low Endotoxin [GK1.5] (ICH1042) , Anti-CD4 In Vivo Antibody - Ultra Low Endotoxin [GK1.5] (ICH1042UL)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage