Anti-CD2 In Vivo Antibody - Low Endotoxin (G11) [ICH1001] ichorbio

product summary

company name :

ichorbio

product type :

antibody

product name :

Anti-CD2 In Vivo Antibody - Low Endotoxin (G11) [ICH1001] ichorbio

catalog :

ICH1001

quantity :

1 mg

price :

80 GBP

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

G11

reactivity :

human

application :

western blot

more info or order :

ichorbio product webpage

product information

Product Type :

Low Endotoxin

ichorbio Cat Number :

ICH1001

Page Title :

Anti-CD2 In Vivo Antibody - Low Endotoxin (G11) [ICH1001] ichorbio

Page Heading :

Anti-CD2 In Vivo Antibody - Low Endotoxin (G11) [ICH1001]

Page Heading :

Bulk anti-CD2 In Vivo Antibody - Low Endotoxin (G11)

Product Benefits :

ichorbio's anti-CD2 In Vivo Antibody - Low Endotoxin (G11) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

Target :

CD2

Clone :

G11

Size1 :

1 mg

Academic Price1 :

80 GBP

Size2 :

5mg

Academic Price2 :

240

Size3 :

25mg

Academic Price3 :

640

Size4 :

50mg

Academic Price4 :

1040

Size5 :

100mg

Academic Price5 :

1600

Isotype :

Mouse IgG2a

Other names :

Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5

UniProt :

P06729

Host :

Mouse

Species Reactivity :

Human

Specificity :

Anti-CD2 In Vivo Antibody - Low Endotoxin (G11) recognizes Human CD2. Anti-Human CD2 recognizes a cell surface glycoprotein (Mr 45-59 kDa) on human lymphocytes

Purification method :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution :

The CD2 antigen is present on approximately 80% of normal peripheral blood lymphocytes, >95% of thymocytes, 100% of mature circulating T-cells and a subset of NK cells.

Background :

Appropriate pairs of anti-CD2 antibodies will stimulate peripheral T-cell proliferation and effector function. The CD2 molecule has been shown to be the receptor for leukocyte function antigen (LFA-3/CD58), the binding of which augments T-cell activation mediated by the T-cell antigen receptor (TCR). Anti-Human CD2 can be used to deplete CD2 positive cells by complement-mediated cytotoxicity. Analyses of NK lymphocyte subsets and identification of lymphomas and leukemias of T-cell origin have been done using Anti-CD2 antibodies.

Concentration :

1.0 - 5.0 mg/ml

Formulation :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

Purity :

>95% by SDS-PAGE and HPLC

Endotoxin :

≤ 1.0 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

Storage :

anti-CD2 In Vivo Antibody - Low Endotoxin (G11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications :

Western Blot, Functional Assays

Application Notes :

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Pricing Note :

Contact for industrial pricing

more info or order :

ichorbio product webpage