Anti-CEP164 [1F3G10] NEW | Ximbio 153780 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CEP164 [1F3G10] NEW

catalog :

153780

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

22897

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-CEP164 [1F3G10] NEW

Catalogue Number :

153780

Applications :

IHC IF IP WB

Antigen/Gene or Protein Targets :

Anti-CEP164 [1F3G10]

Synonyms :

Centrosomal protein of 164 kDa, KIAA1052, NPHP15

Reactivity :

Human

Relevance :

CEP164 plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.

Host :

Mouse

Immunogen :

Recombinant human CEP164 amino acids 6-296 (bacterially expressed from pGEX4T as a GST fusion, then thrombin-cleaved and purified).

Subclass :

IgG1 kappa

Positive Control :

hTERT-RPE1 Cell Line

Molecular Weight (kDa) :

164 kDa (runs c.190)

Myeloma Used :

Sp2/0-Ag14

Research Area :

Cancer, Cell Cycle, Cell Structure and Motility, Metabolism

Notes :

Staining pattern: Centriole distal appendages (mother centriole-specific)

more info or order :

Ximbio product webpage