Anti-Cytochrome P450 1B1 [5D3] | Ximbio 153656 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Cytochrome P450 1B1 [5D3]

catalog :

153656

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1545

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Cytochrome P450 1B1 [5D3]

Catalogue Number :

153656

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Human cytochrome P450 1B1

Synonyms :

Aryl hydrocarbon hydroxylase antibody, CP1B antibody, CP1B1_HUMAN antibody, Cyp1b1 antibody, CYPIB1 antibody, Cytochrome P450 1B1 antibody, Cytochrome P450 family 1 subfamily B polypeptide 1 antibody, Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile) antibody, Flavoprotein linked monooxygenase antibody, GLC3A antibody, Microsomal monooxygenase antibody, P4501B1 antibody, Xenobiotic monooxygenase antibody

Reactivity :

Human

Relevance :

Cytochrome P450 (CYP) 1B1 is overexpressed in tumour cells and is recognised as a biomarker of the tumour phenotype. Recent studies have highlighted the potential of this enzyme as a novel cancer therapeutic target, resulting in several clinical development programs focused on CYP1B1-activated prodrugs and CYP1B1 inhibitors.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide; PENFDPARFLDKDGL (aa. 437-451). Peptide immunogen is identical in mouse (Mus musculus), rat (Rattus norvegicus), dog (Canis familiaris), pig (Sus scrofa) and horse (Equus caballus).

Subclass :

IgG1 kappa

Positive Control :

IHC: formalin-fixed, paraffin-embedded ovarian cancer sections; Western Blot: rhCYP1B1 from lymphoblastoid cells (Gentest); 10mcg microsomal protein / lane

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism, Neurobiology

Notes :

Not reactive with CYP1A1. IHC antigen retrieval: microwave 20 min @ 800W in 10mM citrate buffer, pH 6.0.

more info or order :

Ximbio product webpage