Anti-CD195 [HEK/1/85a/7a] | Ximbio 153524 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD195 [HEK/1/85a/7a]

catalog :

153524

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

1234

reactivity :

human

application :

immunocytochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD195 [HEK/1/85a/7a]

Catalogue Number :

153524

Applications :

FACS IF Fn

Antigen/Gene or Protein Targets :

CD195

Synonyms :

Anti-CCR5, CCR5 Antibody, CD195 Antibody, C-C chemokine receptor type 5, HIV-1 fusion co-receptor

Reactivity :

Human

Relevance :

CD195 or CCR5 (CC-chemokine receptor type 5) is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferation or differentiation, and has been shown to act as a co-receptor for HIV-1 R5 isolates. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.

Host :

Rat

Immunogen :

CHO cells transfected with human CCR5

Subclass :

IgG2a kappa

Myeloma Used :

Y3.AG.1.2.3

Research Area :

Immunology, Virology

more info or order :

Ximbio product webpage