product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-HuD [15A9] (ChIP Grade)
catalog :
153502
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1996
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
product information
Name :
Anti-HuD [15A9] (ChIP Grade)
Catalogue Number :
153502
Applications :
ChIP ELISA IHC IP WB
Antigen/Gene or Protein Targets :
HuD
Synonyms :
ELAV-like protein 4
Reactivity :
Human
Relevance :
HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene. The HuD/ELAVL4 protein is an RNA-binding protein. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity. Monoclonal 15A9 was generated against a unique HuD peptide and does not react with HuR, HuC, or Hel-N1. Monoclonal 15A9 works well in western blot, IHC and provides an excellent marker for neuronal cells. However, it was specifically selected becasue of its abiity to supershift HuD/mRNA ribonucleoprotein complexes. Thus, it is the ideal reagent for CHIP or RIP studies to specifically identify novel HuD targets in neuronal cells.
Host :
Mouse
Subclass :
IgG2b
Research Area :
Developmental Biology, Gene Expression, Neurobiology
more info or order :
company information
Ximbio
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