Anti-Sucrase-Isomaltase [mglu1] | Ximbio 153495 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Sucrase-Isomaltase [mglu1]

catalog :

153495

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6476

reactivity :

human

application :

ELISA, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Sucrase-Isomaltase [mglu1]

Catalogue Number :

153495

Applications :

ELISA IP

Antigen/Gene or Protein Targets :

Sucrase-isomaltase

Synonyms :

Sucrase-isomaltase, CSID, Oligosaccharide alpha 1, 6 glucosidase, AKA: Mglu1 - [3G51/2E10]

Reactivity :

Human

Relevance :

Sucrase-isomaltase is a glucosidase enzyme and type II transmembrane glycoprotein located in the apical brush border membrane of small intestinal enterocytes. Sucrase-isomaltase digests dietary sucrose, maltose and isomaltose, which produces monosaccharides which can be taken up into the enterocytes and ultimately used as a source of energy. Defects in sucrase-isomaltase are the cause of the disease; congenital sucrase-isomaltase deficiency also known as disaccharide intolerance I. This an autosomal recessive intestinal disorder that is clinically characterized by abdominal pain, fermentative diarrhea and cramping.

Host :

Mouse

Immunogen :

Normal human jejunal epithelial brush border-enriched membranes from a non-secretor and blood group O

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 supplemented with 20% Fetal calf Serum medium containing 10-6M thymidine, 1.6x10-7M hypoxanthine and 10-5M methotrexate.

Strain :

Balb/c

Research Area :

Cancer, Cell Signaling & Signal Transduction, Immunology, Metabolism

more info or order :

Ximbio product webpage