product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-IFN-?rel [VAB4P2B4*E8]
catalog :
153451
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VAB4P2B4*E8
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
Name :
Anti-IFN-?rel [VAB4P2B4*E8]
Catalogue Number :
153451
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
Anti-IFN-?rel
Synonyms :
IFG antibody, IFI antibody, IFN gamma antibody, IFN immune antibody, IFN-gamma antibody, IFNG antibody, Immune interferon antibody, Interferon gamma antibody
Reactivity :
Salmon and Brown Trout
Relevance :
Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-? and IFN-?) and type II IFN (IFN-?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-? and IFN-?-related (IFN-?rel). IFN-? and IFN-?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta).
Host :
Mouse
Immunogen :
ovalbumin-conjugated synthetic peptide-DLKRSYYQDR; peptide immunogen is 90% identical to rainbow trout (Oncorhynchus mykiss)
Subclass :
IgG
Positive Control :
Western Blot-IFN-?rel recombinant; IHC- Formalin-fixed, paraffin-embedded fish head kidney and spleen
Molecular Weight (kDa) :
22 kDa
Myeloma Used :
P3X63Ag8.653
Strain :
Balb/c
Research Area :
Aquaculture, Immunology
Notes :
Recommended Usage Conditions: ELISA- neat, Western Blot- neat, IHC- 1/3, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com