Anti-MUC1 [C789] | Ximbio 153397 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MUC1 [C789]

catalog :

153397

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4582

reactivity :

human

application :

immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-MUC1 [C789]

Catalogue Number :

153397

Applications :

IHC

Antigen/Gene or Protein Targets :

MUC1

Synonyms :

CD227; KL6; Mucin 1; PEMT

Reactivity :

Human and Xenopus laevis

Relevance :

MUC1/CA 15-3 is used as a serological clinical marker of breast cancer to monitor response to breast cancer treatment and disease recurrence. Decreased levels over time may be indicative of a positive response to treatment. Conversely, increased levels may indicate disease progression. At an early stage disease, only 21% of patients exhibit high MUC1/CA 15-3 levels, that is why CA 15-3 is not a useful screening test. Most antibodies target the highly immunodominant core peptide domain of 20 amino acid (APDTRPAPGSTAPPAHGVTS) tandem repeats. Some antibodies recognize glycosylated epitopes. Medullary cystic kidney disease 1.

Host :

Mouse

Immunogen :

need access to this paper to answer this - https://www.ncbi.nlm.nih.gov/pubmed/?term=fine+specificity+of+antibody+recognition+of+carcinoma-associated+epithelial+musincs

Molecular Weight (kDa) :

122

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage