Anti-MUC1 [C595 (NCRC48)] | Ximbio 153396 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MUC1 [C595 (NCRC48)]

catalog :

153396

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4582

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-MUC1 [C595 (NCRC48)]

Catalogue Number :

153396

Applications :

ELISA FACS IHC WB

Antigen/Gene or Protein Targets :

MUC1

Synonyms :

CD227; KL6; Mucin 1; PEMT

Reactivity :

Human

Relevance :

MUC1/CA 15-3 is used as a serological clinical marker of breast cancer to monitor response to breast cancer treatment and disease recurrence. Decreased levels over time may be indicative of a positive response to treatment. Conversely, increased levels may indicate disease progression. At an early stage disease, only 21% of patients exhibit high MUC1/CA 15-3 levels, that is why CA 15-3 is not a useful screening test. Most antibodies target the highly immunodominant core peptide domain of 20 amino acid (APDTRPAPGSTAPPAHGVTS) tandem repeats. Some antibodies recognize glycosylated epitopes. Medullary cystic kidney disease 1.

Host :

Mouse

Immunogen :

Urinary MUC-1 mucin (Human)

Subclass :

IgG3

Positive Control :

Breast carcinoma

Molecular Weight (kDa) :

122

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage