Anti-KSR [MINT/1/14] | Ximbio 153392 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-KSR [MINT/1/14]

catalog :

153392

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

8844

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-KSR [MINT/1/14]

Catalogue Number :

153392

Applications :

IHC WB

Antigen/Gene or Protein Targets :

KSR

Synonyms :

RSU2; KSR

Reactivity :

Human, Mouse and Rat

Relevance :

Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity. In unstimulated cells, where the phosphorylated form is bound to a 14-3- 3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery.

Host :

Rat

Immunogen :

Recombinant human KSR protein

Subclass :

IgG2a

Molecular Weight (kDa) :

140

Research Area :

Cancer, Cell Signaling & Signal Transduction

more info or order :

Ximbio product webpage