Anti-EGFR [ICR10] | Ximbio 153386 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-EGFR [ICR10]

catalog :

153386

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

1950

reactivity :

human

application :

western blot, immunohistochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-EGFR [ICR10]

Catalogue Number :

153386

Applications :

FACS IHC WB

Antigen/Gene or Protein Targets :

EGFR

Synonyms :

ERBB1; HER1; epidermal growth factor receptor; ERBB; mENA; PIG61

Reactivity :

Human

Relevance :

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Host :

Rat

Immunogen :

Extracellular domain of human EGF-receptor from head and neck carcinoma

Subclass :

IgG2a

Positive Control :

FACS: A431 cells IHC: Breast Carcinoma tissue WB: HN5 cell lysate

Research Area :

Cancer, Cell Signaling & Signal Transduction

more info or order :

Ximbio product webpage