Anti-IL21 [V28P5G1*C4] | Ximbio 153375 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-IL21 [V28P5G1*C4]

catalog :

153375

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

V28P5G1*C4

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-IL21 [V28P5G1*C4]

Catalogue Number :

153375

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Interleukin 21 (IL21)

Synonyms :

IL 21 antibody, Interleukin 21 antibody, Interleukin21 antibody

Reactivity :

Salmon and Rainbow Trout

Relevance :

IL21 is a member of the type I cytokine family, which includes IL2 and IL15. IL21 signals through the common gamma-chain and a unique IL21 receptor. The IL21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL21 is a key component of CD4 T cell help that is required for maintaining the CD8+ T cell responses and inducing B cell antibody response. IL21 also promotes the development of Th17 and Tfh cells, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. It is also implicated in the development of autoimmune disease and has antitumor activity.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide- LLQKAISRLA

Subclass :

IgG

Positive Control :

Western Blot recombinant IL21; IHC - Formalin-fixed, paraffin-embedded fish head kidney and spleen

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Aquaculture, Cancer, Immunology

Notes :

Recommended Usage Conditions: ELISA - neat Western blot - neat IHC - 1/3 (antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0)

more info or order :

Ximbio product webpage