Anti-IgNAR [V39] | Ximbio 153311 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-IgNAR [V39]

catalog :

153311

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

V39

application :

western blot, ELISA

more info or order :

Ximbio product webpage

product information

Name :

Anti-IgNAR [V39]

Catalogue Number :

153311

Applications :

ELISA WB

Antigen/Gene or Protein Targets :

IgNAR immunoglobulin heavy chain membrane and secretory forms

Synonyms :

Small-spotted catshark IgNAR, IgNAR antibody, Nanobody, Single domain antibody

Reactivity :

Small-spotted catshark

Relevance :

Sharks, and other members in Chondrichthyes, produce, apart from the expected IgM and IgW, a type of ancestral antibody referred to immunoglobulin new antigen receptor (IgNAR). IgNAR antibody is composed of only a homodimeric heavy chain which contains one variable and five constant domains for each chain. The distinct structure of IgNAR domains leads to extremely high stability. In addition, VNAR is around 10 times smaller than standard antibodies and able to continue to function and exist within very extreme conditions. These properties allow IgNAR to penetrate tissues easier in vivo to improve bioavailability for pharmaceutical applications. Anti-IgNAR antibody (V39) can be used to monitor IgNAR levels in shark following immunization

Host :

Mouse

Immunogen :

Ovalbumin-conjugated short synthetic peptide

Subclass :

IgG1

Positive Control :

Western Blot, sera

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Aquaculture

more info or order :

Ximbio product webpage