Anti-C3 [WM1] | Ximbio 153253 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-C3 [WM1]

catalog :

153253

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

718

reactivity :

human

application :

immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-C3 [WM1]

Catalogue Number :

153253

Applications :

IP Fn

Antigen/Gene or Protein Targets :

Human complement component 3

Reactivity :

Human

Relevance :

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Host :

Mouse

Immunogen :

Human complement component 3

Subclass :

IgG1 lambda

Positive Control :

Human primary fibroblasts

Myeloma Used :

P3X63Ag8

Strain :

Balb/c

Research Area :

Cell Type or Organelle Marker, Immunology, Neurobiology, Protein Degradation

Notes :

The antibody will bind to C3b and C3c, but not to C3a or C3d. WM1 antibody inhibits a standard C3 hemolytic assay. The antibody was unable to immunoprecipitate rabbit or mouse C3.

more info or order :

Ximbio product webpage