product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD22 [BU59]
catalog :
153221
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
933
reactivity :
human
application :
immunohistochemistry, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD22 [BU59]
Catalogue Number :
153221
Applications :
FACS IHC
Antigen/Gene or Protein Targets :
CD22
Synonyms :
Cluster of differentiation-22; B cell receptor CD22 precursor;
Reactivity :
Human
Relevance :
Cluster of differentiation 22 (CD22) is a sugar binding transmembrane protein belonging to the SIGLEC family of lectins, found on the surface of mature B cells and on some immature B cells. It acts as by preventing over activation of the immune system and the development of autoimmune diseases. CD22 which binds specifically to sialic acid with its N terminal immunoglobulin domain, is a member of the immunoglobulin superfamily due to the presence of Ig domains. CD22 function’s as an inhibitory receptor for B cell receptor signalling and is also involved in the B cell trafficking to Peyer's patches in mice.
Host :
Mouse
Immunogen :
Tonsil derrived B cells
Subclass :
IgG1
Strain :
Balb/c
Research Area :
Adhesion, Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com