Anti-HLA-DRB1 [DJ9] | Ximbio 153210 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-HLA-DRB1 [DJ9]

catalog :

153210

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

85441

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-HLA-DRB1 [DJ9]

Catalogue Number :

153210

Applications :

FACS IHC IF WB

Antigen/Gene or Protein Targets :

Human major histocompatibility complex class II, DR (HLA-DRB1)

Synonyms :

Major histocompatibility complex, class II, DRB1

Reactivity :

Human

Relevance :

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. HLA-DRB1 binds peptides derived from antigens that access the endocytic route of antigen presenting cells and presents them on the cell surface for recognition by the CD4 T-cells. Class II molecules are expressed in antigen presenting cells B lymphocytes, dendritic cells, macrophages. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-DRB1, clone DJ9, has been shown to be a relevant marker of bone marrow derived mesenchymal stem cells and their osteogenic derivatives (Andersen, D., et al., 2011).

Host :

Mouse

Immunogen :

Whole, intact hMSC-TERT Cells

Subclass :

IgG2a lambda

Research Area :

Immunology

Notes :

Epitope: The epitope is on the extracellular side of the HLA-DRB1 molecule

more info or order :

Ximbio product webpage