Anti-SMC3 [DJ5.2.3] | Ximbio 153176 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-SMC3 [DJ5.2.3]

catalog :

153176

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9126

reactivity :

human, mouse

application :

western blot

more info or order :

Ximbio product webpage

product information

Name :

Anti-SMC3 [DJ5.2.3]

Catalogue Number :

153176

Applications :

Antigen/Gene or Protein Targets :

SMC3

Reactivity :

Xenopus laevis, Human and Mouse

Relevance :

SMC3 is a central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.

Host :

Mouse

Immunogen :

Synthetic peptide - EEVSLRRVIGAKacetyl Kacetyl DQYFLDKK

Positive Control :

Xenopus chromatin extract

Molecular Weight (kDa) :

141

Research Area :

Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

Raised from mice immunized with the peptide sequence: EEVSLRRVIGAKKDQYFLDKK corrosponding to amino acids 94 -114 of Xenopus laevis SMC3 DJ5.2.3 reacts against SMC3 from Xenopus, human and mouse.

more info or order :

Ximbio product webpage