Anti-GFAP [FD19-9] | Ximbio 152989 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-GFAP [FD19-9]

catalog :

152989

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2670

reactivity :

human

application :

immunohistochemistry, immunocytochemistry

more info or order :

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product information

Name :

Anti-GFAP [FD19-9]

Catalogue Number :

152989

Applications :

IHC IF

Antigen/Gene or Protein Targets :

Glial fibrillary acid protein

Synonyms :

wu:fb34h11, ALXDRD, cb345, etID36982.3, FLJ42474, FLJ45472, GFAP, GFAP_HUMAN, gfapl, Glial fibrillary acidic protein, Intermediate filament protein, wu:fk42c12, xx:af506734, zgc:110485

Reactivity :

Human

Relevance :

Glial fibrillary acidic protein, or GFAP, is an intermediate filament (IF) protein belonging to the type III subclass of IF proteins. Like other IF proteins, GFAP is composed of an amino terminal head domain, central rod domain and a carboxy terminal tail domain. GFAP is specifically found in astroglia, a cell type which is highly responsive to neurologic insults. Astrogliosis is found to be a result of mechanical trauma, AIDS dementia, prion infection and inflammatory demylination diseases, and is accompanied by an increase in GFAP expression. GFAP is an immunohistochemical marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system.

Host :

Mouse

Immunogen :

Relatively benign cerebellar astrocytoma from 5 year old child.

Subclass :

IgG1

Positive Control :

HeLa whole cell lysate

Molecular Weight (kDa) :

Myeloma Used :

P3X63Ag8

Strain :

Balb/c

Research Area :

Adhesion, Cell Signaling & Signal Transduction, Neurobiology, Stem Cell Biology

more info or order :

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