Anti-CD11b [2LPM19c] | Ximbio 152935 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD11b [2LPM19c]

catalog :

152935

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3684

reactivity :

human

application :

immunohistochemistry, FACS

more info or order :

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product information

Name :

Anti-CD11b [2LPM19c]

Catalogue Number :

152935

Applications :

FACS IHC

Antigen/Gene or Protein Targets :

Cluster of Differentiation 11b (CD11b)

Synonyms :

CD11b, Integrin alpha M, Integrin aM, Mac-1 a subunit, C3bi receptor, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor

Reactivity :

Human

Relevance :

CD11b, also known as Integrin alpha M, is found in neutrophils, monocytes and Natural Killer (NK) cells. CD11b plays a role in chemotaxis, apoptosis and phagocytosis. It is absent in Leukocyte Adhesion Deficiency (LAD-1) and is a target for anti-inflammatory drug therapies. CD11b is part of the CD11b/CD18 heterodimer (Mac-1 a, Mß2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain.

Host :

Mouse

Immunogen :

Purified C3bi receptor

Subclass :

IgG1 kappa

Molecular Weight (kDa) :

127

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + glutamine (2mM) + HAT

Research Area :

Adhesion, Apoptosis and Programmed Cell Death, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Neurobiology, Stem Cell Biology

more info or order :

Ximbio product webpage