product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-RAD53 [EL7-E1]
catalog :
152920
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
EL7-E1
application :
western blot
more info or order :
product information
Name :
Anti-RAD53 [EL7-E1]
Catalogue Number :
152920
Applications :
WB
Antigen/Gene or Protein Targets :
RAD53
Synonyms :
Checkpoint Kinase 2; CHK2 Checkpoint Homolog; Cds1 Homolog; HuCds1; RAD53; HCds1; CDS1; CHK2; Checkpoint-Like Protein CHK2; PP1425; LFS2
Reactivity :
Saccharomyces cerevisiae
Relevance :
RAD53 is a serine/threonine-protein kinase that controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. RAD53 phosphorylates proteins on serine, threonine, and tyrosine amino acids. It prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. RAD53 seems to be involved in the phosphorylation of histone demethylase RPH1.
Host :
Mouse
Myeloma Used :
Sp2/0
Research Area :
Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com