Anti-Cmt2 [I3-4-14] | Ximbio 152906 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Cmt2 [I3-4-14]

catalog :

152906

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

I3-4-14

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Cmt2 [I3-4-14]

Catalogue Number :

152906

Applications :

IF IP WB

Antigen/Gene or Protein Targets :

p31 comet

Relevance :

CMT2, KIF1B, or kinesin-like protein (Klp) functions as a motor for mitochondrial transport, and has a microtubule plus end-directed motility. The KIF1B beta isoform is abundant in brain, while the alpha isoform is abundant in skeletal muscle. Mutations in the KIF1B gene are the cause of Charcot-Marie-Tooth disease type 2A1, which is a primary peripheral axon neuropathy. The KIF1B beta isoform is down-regulated in sporadic amyotrophic lateral sclerosis (ALS).

Host :

Mouse

Myeloma Used :

Sp2/0

Research Area :

Adhesion, Cell Signaling & Signal Transduction, Cell Structure and Motility, Neurobiology

more info or order :

Ximbio product webpage