product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-TERF1 [BED5-57-6]
catalog :
152896
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
29893
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
Name :
Anti-TERF1 [BED5-57-6]
Catalogue Number :
152896
Applications :
WB
Antigen/Gene or Protein Targets :
NIMA interacting 1
Synonyms :
hTRF1 AS, NIMA interacting protein 2, NIMA-interacting protein 2, PIN 2, PIN2, t TRF1, Telomeric protein Pin2, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor (NIMA interacting) 1, Telomeric repeat binding factor 1, Telomeric repeat binding protein 1
Reactivity :
Human, Mouse, Mouse and Rat
Relevance :
Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
Host :
Mouse
Subclass :
IgG1 kappa
Myeloma Used :
Sp2/0
Research Area :
Cancer, Cell Type or Organelle Marker, DNA Damage and Repair, Epigenetics & Nuclear Signalling
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com