Anti-Mad1 [BB3-8] | Ximbio 152879 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Mad1 [BB3-8]

catalog :

152879

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

954

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Mad1 [BB3-8]

Catalogue Number :

152879

Applications :

IF IP WB

Antigen/Gene or Protein Targets :

Mitotic Arrest De?cientl like 1

Synonyms :

hMAD1, HsMAD1, MAD1, MAD1 mitotic arrest deficient like 1 (yeast), MAD1-like protein 1, MAD1L1, MD1L1_HUMAN, Mitotic arrest deficient 1, Mitotic arrest deficient 1-like protein 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, PIG9, Tax binding protein 181, Tax-binding protein 181, TP53I9, Tumor protein p53 inducible protein 9, TXBP181

Reactivity :

Human

Relevance :

Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.

Host :

Mouse

Subclass :

IgG1 kappa

Myeloma Used :

Sp2/0

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage