Anti-CHL1 [BB13.13] | Ximbio 152868 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CHL1 [BB13.13]

catalog :

152868

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

16728

reactivity :

mouse

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-CHL1 [BB13.13]

Catalogue Number :

152868

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

Cell adhesion molecule with homology to L1CAM

Reactivity :

Mouse

Relevance :

CHL1 is an extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. CHL1 plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. CHL1 may play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins and recruits ANK3 to the plasma membrane.

Host :

Rat

Myeloma Used :

Sp2/0

Research Area :

Adhesion, Cell Signaling & Signal Transduction, Neurobiology

more info or order :

Ximbio product webpage